HAL will be down for maintenance from Friday, June 10 at 4pm through Monday, June 13 at 9am. More information
Skip to Main content Skip to Navigation
Journal articles

Spinal sensory circuits in motion

Abstract : The role of sensory feedback in shaping locomotion has been long debated. Recent advances in genetics and behavior analysis revealed the importance of proprioceptive pathways in spinal circuits. The mechanisms underlying peripheral mechanosensation enabled to unravel the networks that feedback to spinal circuits in order to modulate locomotion. Sensory inputs to the vertebrate spinal cord were long thought to originate from the periphery. Recent studies challenge this view: GABAergic sensory neurons located within the spinal cord have been shown to relay mechanical and chemical information from the cerebrospinal fluid to motor circuits. Innovative approaches combining genetics, quantitative analysis of behavior and optogenetics now allow probing the contribution of these sensory feedback pathways to locomotion and recovery following spinal cord injury.
Document type :
Journal articles
Complete list of metadata

Cited literature [44 references]  Display  Hide  Download

https://hal.sorbonne-universite.fr/hal-01371943
Contributor : Gestionnaire 2 Hal-Upmc Connect in order to contact the contributor
Submitted on : Monday, September 26, 2016 - 4:11:12 PM
Last modification on : Saturday, May 21, 2022 - 3:42:01 AM

File

Bohm_2016_Spinal_sensory.pdf
Files produced by the author(s)

Identifiers

Citation

Urs Lucas Böhm, Claire Wyart. Spinal sensory circuits in motion. Current Opinion in Neurobiology, Elsevier, 2016, 41, pp.38-43. ⟨10.1016/j.conb.2016.07.007⟩. ⟨hal-01371943⟩

Share

Metrics

Record views

181

Files downloads

306