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Hyperthermia Efficiency of Magnetic Nanoparticles in Dense Aggregates of Cerium Oxide/Iron Oxide Nanoparticles

Abstract : Iron oxide nanoparticles are intended to be used in bio-applications for drug delivery associated with hyperthermia. However, their interactions with complex media often induces aggregation, and thus a detrimental decrease of their heating efficiency. We have investigated the role of iron oxide nanoparticles dispersion into dense aggregates composed with magnetic/non-magnetic nanoparticles and showed that, when iron oxide nanoparticles were well-distributed into the aggregates, the specific absorption rate reached 79% of the value measured for the well-dispersed case. This study should have a strong impact on the applications of magnetic nanoparticles into nanostructured materials for therapy or catalysis applications.
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Cindy Yadel, Aude Michel, Sandra Casale, Jérôme Fresnais. Hyperthermia Efficiency of Magnetic Nanoparticles in Dense Aggregates of Cerium Oxide/Iron Oxide Nanoparticles. Applied Sciences, MDPI, 2018, 8 (8), pp.1241. ⟨10.3390/app8081241⟩. ⟨hal-01875545⟩

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