Trial watch: dietary interventions for cancer therapy - Sorbonne Université
Article Dans Une Revue OncoImmunology Année : 2019

Trial watch: dietary interventions for cancer therapy

Résumé

Dietary interventions have a profound impact on whole body metabolism, including oncometabolism (the metabolic features allowing cancer cells to proliferate) and immunometabolism (the catabolic and anabolic reactions that regulate immune responses). Recent preclinical studies demonstrated that multiple dietary changes can improve anticancer immunosurveillance of chemo-, radio- and immunotherapy. These findings have fostered the design of clinical trials evaluating the capacity of dietary interventions to synergize with treatment and hence limit tumor progression. Here, we discuss the scientific rationale for harnessing dietary interventions to improve the efficacy of anticancer therapy and present up-to-date information on clinical trials currently investigating this possibility.
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Dates et versions

hal-02147212 , version 1 (04-06-2019)

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Sarah Levesque, Jonathan G Pol, Gladys Ferrere, Lorenzo Galluzzi, Laurence Zitvogel, et al.. Trial watch: dietary interventions for cancer therapy. OncoImmunology, 2019, 8 (7), pp.1591878. ⟨10.1080/2162402X.2019.1591878⟩. ⟨hal-02147212⟩
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