While a lot of work is needed to figure out the organic-silica interfaces in natural materials such as diatom frustules or marine siliceous sponge spicules, Solid-State NMR appears to be a powerful toolbox with several nuclei and methods to carry out. Nevertheless, natural abundance in 13 C as well as a too poor C-content in the cleaned specimen do not allow nor 2D correlations neither well-resolved 1D spectra, that are necessary to go further on species proximity and connectivity assessment. Conjugating DNP to SS-NMR appears to be a promising solution to enhance the signal.