Four core properties of the human brain valuation system demonstrated in intracranial signals - Sorbonne Université
Journal Articles Nature Neuroscience Year : 2020

Four core properties of the human brain valuation system demonstrated in intracranial signals

Julien Bastin

Abstract

Estimating the value of alternative options is a key process in decision-making. Human functional magnetic resonance imaging and monkey electrophysiology studies have identified brain regions, such as the ventromedial prefrontal cortex (vmPFC) and lateral orbitofrontal cortex (lOFC), composing a value system. In the present study, in an effort to bridge across species and techniques, we investigated the neural representation of value ratings in 36 people with epilepsy, using intracranial electroencephalography. We found that subjective value was positively reflected in both vmPFC and lOFC high-frequency activity, plus several other brain regions, including the hippocampus. We then demonstrated that subjective value could be decoded (1) in pre-stimulus activity, (2) for various categories of items, (3) even during a distractive task and (4) as both linear and quadratic signals (encoding both value and confidence). Thus, our findings specify key functional properties of neural value signals (anticipation, generality, automaticity, quadraticity), which might provide insights into human irrational choice behaviors.
Fichier principal
Vignette du fichier
Lopez-Persem_iEEG_NatNeuro_complete.pdf (7.61 Mo) Télécharger le fichier
Origin Files produced by the author(s)
Loading...

Dates and versions

hal-02881927 , version 1 (26-06-2020)

Identifiers

Cite

Alizée Lopez-Persem, Julien Bastin, Mathilde Petton, Raphaëlle Abitbol, Katia Lehongre, et al.. Four core properties of the human brain valuation system demonstrated in intracranial signals. Nature Neuroscience, 2020, 23 (5), pp.664-675. ⟨10.1038/s41593-020-0615-9⟩. ⟨hal-02881927⟩
278 View
818 Download

Altmetric

Share

More