Marine prokaryotes represent abundant and diverse communities across oceans. These organisms are free living, symbionts, parasites or or produce biofilm on very diverse types of marine surfaces. These surfaces include micro- and macro-algae leaves (phycosphere), marine particles, seashore rocks, buoys, microplastics and many others. Such niches favor bacterial concentration and thus different types of bacterial interactions, including quorum sensing. This consists of a mechanism that allows cells to coordinate their gene expression and physiology when a defined number of cells is reached. This review aims to synthesize quorum sensing mechanisms evidenced to date in the marine biofilms and environments. It will first focus on the wide range of chemical compounds involved in these processes and will describe the diversity of bacterial functions regulated by quorum sensing. Then, the implications of quorum sensing at a larger and integrated scale will be examined, including potential biogeochemical implication of quorum sensing expression. Also the importance in quorum sensing in the functioning of diverse holobionts will be addressed, as well as potential industrial applications. Overall, this review will emphasize quorum sensing roles at each stage of biofilm development, whatever the type of marine surfaces on which prokaryotes grow or the host they colonize: crucial in the settlement, maturation and dispersion of marine biofilms.