Derivation, Validation, and Prognostic Utility of a Prediction Rule for Nonresponse to Clopidogrel - Sorbonne Université
Journal Articles JACC: Cardiovascular Interventions Year : 2020

Derivation, Validation, and Prognostic Utility of a Prediction Rule for Nonresponse to Clopidogrel

Derivation, Validation, and Prognostic Utility of a Prediction Rule for Nonresponse to Clopidogrel: The ABCD-GENE Score.

Dominick Angiolillo
  • Function : Author
Davide Capodanno
  • Function : Author
Nicolas Danchin
  • Function : Author
Tabassome Simon
Thomas Bergmeijer
  • Function : Author
Jurrien ten Berg
  • Function : Author
Dirk Sibbing
Matthew Price
  • Function : Author

Abstract

The aim of this study was to develop a risk score integrating cytochrome P450 2C19 loss-of-function genotypes with clinical risk factors influencing clopidogrel response that would allow the identification with more precision of subjects at risk for high platelet reactivity (HPR) and adverse clinical outcomes.

Dates and versions

hal-03030882 , version 1 (30-11-2020)

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Cite

Dominick Angiolillo, Davide Capodanno, Nicolas Danchin, Tabassome Simon, Thomas Bergmeijer, et al.. Derivation, Validation, and Prognostic Utility of a Prediction Rule for Nonresponse to Clopidogrel. JACC: Cardiovascular Interventions, 2020, 13 (5), pp.606-617. ⟨10.1016/j.jcin.2020.01.226⟩. ⟨hal-03030882⟩
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