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Journal articles

Engineering glowing chemogenetic hybrids for spying on cells

Abstract : Seeing biochemical events is essential to understand the functioning of cells and organisms. Such imaging depends on the selective targeting of fluorescent reporters and biosensors in living systems. These reporters and biosensors can be entirely synthetic, entirely genetically encoded or hybrid. Hybrid reporters and biosensors composed of a genetically encoded module that binds a fluorogenic chromophore and activates its fluorescence have recently drawn attention as they offer new opportunities for pushing the frontiers of bioimaging.
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Submitted on : Tuesday, December 1, 2020 - 12:53:18 PM
Last modification on : Friday, March 18, 2022 - 3:37:52 AM
Long-term archiving on: : Tuesday, March 2, 2021 - 7:06:58 PM


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Hela Ben Aissa, Arnaud Gautier. Engineering glowing chemogenetic hybrids for spying on cells. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2020, ⟨10.1002/ejoc.202000340⟩. ⟨hal-03033405⟩



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