The protection of aquifers is a major concern for the authorities, especially in areas where there are large agro-industrial exploitations. The objective of this study is to define a new method of aquifer protection based on the characteristics of the structures of aquifers. The intrinsic vulnerability mapping method, PaPRI was used. It is a variant of the PaPRIKa method applied in karstic environment which has been adapted for its application in basement environment. This method uses three factors, including aquifer protection (P), using the soil cover, the unsaturated zone and the thickness of the alteration layer, (R) for the rock type and (I) for infiltration which including slope and drainage density. PAPRI is a method based on the weighting of different factors. The results obtained show 4 classes that evolve from low vulnerability classes (5% of the study area) to high and very high vulnerability classes (58%) and average vulnerability classes (37%). The classes of high and very high vulnerability, which indicate the zones that are very exposed to pollution, are more present in the central-northern part of the study area, with a few appearances towards the south. These zones could be related to topography due to the often very high slopes observed in the area. One of the advantages of this new method lies in the characterization of the alterations that strongly influence the migration of pollutants towards the water tables according to their nature and their thickness.