Cyber physical systems are built upon digital and analog circuits, making it necessary to handle different models of computation during their design and verification (e.g., by simulation). When designing these systems, an important aspect to consider is the causality between the different domains. For this, we introduce a new model-driven framework able to identify causality problems and to suggest a valid schedule between the analog and digital domains. Once a valid schedule has been computed, our framework can generate cycle and bit accurate virtual prototypes (in SystemC/SystemC AMS) from high-level SysML models.