Dynamics of B cell repertoires and emergence of cross-reactive responses in patients with different severities of COVID-19 - Sorbonne Université
Journal Articles Cell Reports Year : 2021

Dynamics of B cell repertoires and emergence of cross-reactive responses in patients with different severities of COVID-19

Abstract

Dynamics of B cell repertoires and emergence of cross-reactive responses in patients with different severities of COVID-19 Graphical abstract Highlights d Analysis of B cell repertoires with SARS-CoV-2 epitopesorted B cell receptors d Differential sequence features of B cell receptors are associated with disease severity d Expansion of B cell clonal lineages in response to SARS-CoV-2 d Shared B cell receptors emerge with cross-reactivity to SARS-CoV-1 and SARS-CoV-2

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Santé publique et épidémiologie Virology
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Submitted on : Friday, June 18, 2021-9:31:24 AM

Last modification on : Friday, April 19, 2024-4:18:59 PM

Long-term archiving on : Sunday, September 19, 2021-6:16:06 PM

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hal-03264272 , version 1 (18-06-2021)

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Zachary Montague, Huibin Lv, Jakub Otwinowski, William S Dewitt, Giulio Isacchini, et al.. Dynamics of B cell repertoires and emergence of cross-reactive responses in patients with different severities of COVID-19. Cell Reports, 2021, 35 (8), pp.109173. ⟨10.1016/j.celrep.2021.109173⟩. ⟨hal-03264272⟩

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