Dynamics of B cell repertoires and emergence of cross-reactive responses in patients with different severities of COVID-19 - Sorbonne Université
Article Dans Une Revue Cell Reports Année : 2021

Dynamics of B cell repertoires and emergence of cross-reactive responses in patients with different severities of COVID-19

Résumé

Dynamics of B cell repertoires and emergence of cross-reactive responses in patients with different severities of COVID-19 Graphical abstract Highlights d Analysis of B cell repertoires with SARS-CoV-2 epitopesorted B cell receptors d Differential sequence features of B cell receptors are associated with disease severity d Expansion of B cell clonal lineages in response to SARS-CoV-2 d Shared B cell receptors emerge with cross-reactivity to SARS-CoV-1 and SARS-CoV-2
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Dates et versions

hal-03264272 , version 1 (18-06-2021)

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Zachary Montague, Huibin Lv, Jakub Otwinowski, William S Dewitt, Giulio Isacchini, et al.. Dynamics of B cell repertoires and emergence of cross-reactive responses in patients with different severities of COVID-19. Cell Reports, 2021, 35 (8), pp.109173. ⟨10.1016/j.celrep.2021.109173⟩. ⟨hal-03264272⟩
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