Social inequalities in health and their early life origins have been extensively documented. Although the complex direct and intermediate mechanisms linking early life disadvantage to later health are not yet fully understood, new findings on biological markers distinctly related with early life experiences suggest a causal relation. In their paper, Fuller-Rowell et al step back to examine the role of childhood disadvantage in the United States in different periods, and observe that the relationship with later health seems to have strengthened over time. The main explanation the authors bring up has to do with increased income segregation and changes in labour market composition which limit opportunities for persons with low educational attainment. In other words, while the rich get richer, the poor get poorer, the middle class shrinks, and there are fewer interactions across different socio-economic groups and the social ladder is blocked. Other evidence suggests that investments in children, through early education and academic support programs, could help reduce the consequences of childhood disadvantage on long-term health.