Using micro computed tomographic imaging for analyzing kidney stones - Sorbonne Université
Journal Articles Comptes Rendus. Chimie Year : 2022

Using micro computed tomographic imaging for analyzing kidney stones

Abstract

Stone analysis is a critical part of the clinical characterization of urolithiasis. This article reviews the strengths and limitations of micro CT in the analysis of stones. Using micro CT alone in a series of 757 stone specimens, micro CT identified the 458 majority calcium oxalate specimens with a sensitivity of 99.6% and specificity of 95.3%. Micro CT alone was also successful in identifying majority apatite, brushite, uric acid, and struvite stones. For some minor minerals-such as apatite in calcium oxalate or calcium salts in uric acid stones-micro CT enables the detection of minute quantities well below 1%. The addition of a standard for calibrating X-ray attenuation values improves the ability of micro CT to identify common stone minerals. The three-dimensional nature of micro CT also allows for the visualization of surface features in stones, which is valuable for the study of stone formation.
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Dates and versions

hal-03335928 , version 1 (06-09-2021)

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James C Williams, James E Lingeman, Michel Daudon, Dominique Bazin. Using micro computed tomographic imaging for analyzing kidney stones. Comptes Rendus. Chimie, 2022, 25 (S2), pp.61-72. ⟨10.5802/crchim.89⟩. ⟨hal-03335928⟩
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