Percutaneous Image-Guided Vertebral Fixation in Cancer-Related Vertebral Compression Fractures: A Case Series Study - Sorbonne Université
Journal Articles Medicina Year : 2021

Percutaneous Image-Guided Vertebral Fixation in Cancer-Related Vertebral Compression Fractures: A Case Series Study

Francois H Cornelis
Leo Razakamanantsoa
  • Function : Author
  • PersonId : 1101061
Milan Najdawi
  • Function : Author
  • PersonId : 1101064
Francois Gardavaud
Sanaa El-Mouhadi
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  • PersonId : 1101063
Matthias Barral
  • Function : Author
  • PersonId : 1101065

Abstract

Background and objectives: Cancer-related vertebral compression fractures (VCF) may cause debilitating back pain and instability, affecting the quality of life of cancer patients. To further drive cement deposition during vertebroplasty, the aims of this restrospective case series study were to report the feasibility, safety and short term efficacy (≤6 months) of percutaneous vertebral fixation in cancer-related vertebral compression fractures using various intravertebral implants. Methods: All consecutive cancer patients treated with percutaneous vertebral fixation for VCF were retrospectively included. Various devices were inserted percutaneously under image guidance and filled by cement. Descriptive statistics were used and a matched paired analysis of pain scores was performed to assess for changes following interventions. Results: A total of 18 consecutive patients (12 women (66.6%) and 6 men (33.3%); mean age 59.7 ± 15.5 years) were included. A total of 42 devices were inserted in 8 thoracic and 16 lumbar vertebrae. Visual analogue scale measurement significantly improved from 5.6 ± 1.8 preoperatively to 1.5 ± 1.7 at 1 week (p < 0.01) and to 1.5 ± 1.3 at 6 months (p < 0.01). No severe adverse events were observed, but three adjacent fractures occurred between 1 week and 5 months after implantation. Conclusions: Percutaneous vertebral fixation of cancer-related VCF is feasible and safe and allows pain relief.
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Dates and versions

hal-03351542 , version 1 (22-09-2021)

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Francois H Cornelis, Leo Razakamanantsoa, Mohamed Ben Ammar, Milan Najdawi, Francois Gardavaud, et al.. Percutaneous Image-Guided Vertebral Fixation in Cancer-Related Vertebral Compression Fractures: A Case Series Study. Medicina, 2021, 57 (9), pp.907. ⟨10.3390/medicina57090907⟩. ⟨hal-03351542⟩
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