Improving tumor budding reporting in colorectal cancer: a Delphi consensus study - Sorbonne Université
Journal Articles Virchows Archiv Year : 2021

Improving tumor budding reporting in colorectal cancer: a Delphi consensus study

Hala El-Zimaity
  • Function : Author
Michael Vieth

Abstract

Tumor budding is a long-established independent adverse prognostic marker in colorectal cancer, yet methods for its assessment have varied widely. In an effort to standardize its reporting, a group of experts met in Bern, Switzerland, in 2016 to reach consensus on a single, international, evidence-based method for tumor budding assessment and reporting (International Tumor Budding Consensus Conference [ITBCC]). Tumor budding assessment using the ITBCC criteria has been validated in large cohorts of cancer patients and incorporated into several international colorectal cancer pathology and clinical guidelines. With the wider reporting of tumor budding, new issues have emerged that require further clarification. To better inform researchers and health-care professionals on these issues, an international group of experts in gastrointestinal pathology participated in a modified Delphi process to generate consensus and highlight areas requiring further research. This effort serves to re-affirm the importance of tumor budding in colorectal cancer and support its continued use in routine clinical practice.
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Dates and versions

hal-03371295 , version 1 (08-10-2021)

Identifiers

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Tariq Sami Haddad, Alessandro Lugli, Susan Aherne, Valeria Barresi, Benoît Terris, et al.. Improving tumor budding reporting in colorectal cancer: a Delphi consensus study. Virchows Archiv, 2021, 479 (3), pp.459-469. ⟨10.1007/s00428-021-03059-9⟩. ⟨hal-03371295⟩
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