Treatment for COVID-19—a cohort study from Northern Italy - Sorbonne Université
Article Dans Une Revue Scientific Reports Année : 2021

Treatment for COVID-19—a cohort study from Northern Italy

Résumé

Multicentre, retrospective cohort study with multivariable Cox proportional-hazards modelling and survival-time inverse-probability-weighting, evaluating the impact of different treatments on survival of proven COVID-19 patients admitted to two Hospitals in the province of Piacenza, Italy. Use of tocilizumab and of high doses of low molecular weight heparin, but not of antivirals (either alone or in combination), azithromycin, and any corticosteroid, was independently associated with lower mortality. Our results support further clinical evaluation of high doses of low molecular weight heparin and tocilizumab as COVID-19 therapeutics.
Fichier principal
Vignette du fichier
s41598-021-00243-4.pdf (833.83 Ko) Télécharger le fichier
Origine Publication financée par une institution

Dates et versions

hal-03405979 , version 1 (27-10-2021)

Identifiants

Citer

Lorenzo Guglielmetti, Daniela Aschieri, Irina Kontsevaya, Francesco Calabrese, Alessandra Donisi, et al.. Treatment for COVID-19—a cohort study from Northern Italy. Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-00243-4⟩. ⟨hal-03405979⟩
51 Consultations
33 Téléchargements

Altmetric

Partager

More