Small cell lung cancer responds to immunogenic chemotherapy followed by PD-1 blockade - Sorbonne Université
Journal Articles OncoImmunology Year : 2021

Small cell lung cancer responds to immunogenic chemotherapy followed by PD-1 blockade

Abstract

Sequential combination of immunogenic cell death (ICD)-induced interventions with subsequent immunotherapy has shown efficacy in preclinical models and clinical evaluation. Recently, a clinical trial enrolling small cell lung cancer patients treated with amrubicin together with PD-1 blockade confirmed the notion that ICD sensitizes tumors to immune checkpoint inhibitors.

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Cancer
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Dates and versions

hal-03426432 , version 1 (12-11-2021)

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Guido Kroemer, Oliver Kepp. Small cell lung cancer responds to immunogenic chemotherapy followed by PD-1 blockade. OncoImmunology, 2021, 10 (1), ⟨10.1080/2162402x.2021.1996686⟩. ⟨hal-03426432⟩
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