Objective Hospital readmissions are common in the older adult population and potentially inappropriate medications are known to be involved in these readmissions. Several lists of potentially inappropriate medications have been published in diverse countries in order to adapt the lists to local specificities. Among them, the Beers Criteria® were first published in 1991 in the USA, followed by the French Laroche list, the Norwegian NORGEP criteria, the German PRISCUS list, the the Austrian consensus panel listand the European list, EU-7. The main objective was to detect which potentially inappropriate medications list can better detect hospital readmissions within 30 days in the older adult population hospitalized for fall related injuries. Methods A multicenter observational retrospective cohort study was conducted. Data from older patients initially hospitalized for falls in 2019 and discharged home, were retrieved from the clinical data warehouse. Exposure to potentially inappropriate medications was classified according to the six lists mentioned above. Results After adjustments using propensity score matching, taking a potentially inappropriate medication as per Laroche and PRISCUS lists was associated with a 30-day hospital readmission with an OR of 1.58 (95 % CI [1.06-2.37]) and 1.68 (95 % CI [1.13-2.50]) respectively while the other 4 studied lists showed no association with readmissions. Conclusion Our study evidenced that not all lists published allow the accurate prediction of hospital readmissions to the same extent. We found that Laroche and PRISCUS lists were associated with increased 30day all-cause hospital readmissions after an index admission with a FRI. The local ethic committee approved the study protocol (number CER-2020-79).