Immune sunrise: from the immunome to the cancer immune landscape - Sorbonne Université
Journal Articles OncoImmunology Year : 2022

Immune sunrise: from the immunome to the cancer immune landscape

Abstract

The complex dynamics of the tumor-immune interaction during tumor progression have been characterized by integrating genomic and proteomic experiments. The Immunome, a reference compendium of markers for the majority of immune cell subpopulations was used to describe the immune landscape in cancer. The immune contexture is at the cornerstone in the success of cancer immunotherapies. Markers with the highest clinical relevance were summarized as the consensus immunoscore. This immune evaluation refines the prognosis of the patients and the chemotherapy decision-making process and was introduced as essential and desirable diagnostic criteria into three major international guidelines.
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Dates and versions

hal-03566238 , version 1 (11-02-2022)

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Gabriela Bindea, Bernhard Mlecnik, Jérôme Galon. Immune sunrise: from the immunome to the cancer immune landscape. OncoImmunology, 2022, 11 (1), ⟨10.1080/2162402x.2021.2019896⟩. ⟨hal-03566238⟩
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