Comparison of Kaposi Sarcoma Risk in Human Immunodeficiency Virus-Positive Adults Across 5 Continents: A Multiregional Multicohort Study - Sorbonne Université
Journal Articles Clinical Infectious Diseases Year : 2017

Comparison of Kaposi Sarcoma Risk in Human Immunodeficiency Virus-Positive Adults Across 5 Continents: A Multiregional Multicohort Study

Ali Judd , Robert Zangerle , Giota Touloumi , Josiane Warszawski , Laurence Meyer , François Dabis , Murielle Mary Krause , Jade Ghosn , Catherine Leport , Linda Wittkop , Peter Reiss , Ferdinand Wit , Maria Prins , Heiner Bucher , Diana Gibb , Gerd Fätkenheuer , del Amo Julia , Niels Obel , Claire Thorne , Amanda Mocroft , Ole Kirk , Christoph Stephan , Santiago Pérez-Hoyos , Osamah Hamouda , Barbara Bartmeyer , Nikoloz Chkhartishvili , Antoni Noguera-Julian , Andrea Antinori , Antonella D’arminio Monforte , Norbert Brockmeyer , Luis Prieto , Pablo Rojo Conejo , Antoni Soriano-Arandes , Manuel Battegay , Roger Kouyos , Cristina Mussini , Pat Tookey , Jordi Casabona , Jose M Miró , Antonella Castagna , Deborah Konopnick , Tessa Goetghebuer , Anders Sönnerborg , Eugenia Quiros-Roldan , Caroline Sabin , Ramon Teira , Myriam Garrido , David Haerry , Stéphane de Wit , Jose M Miró , Dominique Costagliola , Antonella D’arminio-Monforte , Antonella Castagna , Julia del Amo , Amanda Mocroft , Dorthe Raben , Geneviève Chêne , Ali Judd , Conejo Pablo Rojo , Diana Barger , Christine Schwimmer , Monique Termote , Linda Wittkop , Maria Campbell , Casper M Frederiksen , Nina Friis-Møller , Jesper Kjaer , Dorthe Raben , Rikke Salbøl Brandt , Juan Berenguer , Julia Bohlius , Vincent Bouteloup , Heiner Bucher , Alessandro Cozzi-Lepri , François Dabis , Antonella D’arminio Monforte , Mary-Anne Davies , Julia del Amo , Maria Dorrucci , David Dunn , Matthias Egger , Hansjakob Furrer , Sophie Grabar (1) , Marguerite Guiguet , Ali Judd , Ole Kirk , Olivier Lambotte , Valériane Leroy , Sara Lodi , Sophie Matheron , Laurence Meyer , Jose M Miró , Amanda Mocroft , Susana Monge , Fumiyo Nakagawa , Roger Paredes , Andrew Phillips , Massimo Puoti , Eliane Rohner , Michael Schomaker , Colette Smit , Jonathan Sterne , Rodolphe Thiebaut , Claire Thorne , Carlo Torti , Marc van der Valk , Linda Wittkop , Frank Tanser , Michael Vinikoor , Eusebio Macete , Robin Wood , Kathryn Stinson , Daniela Garone , Geoffrey Fatti , Janet Giddy , Kennedy Malisita , Brian Eley , Christiane Fritz , Michael Hobbins , Kamelia Kamenova , Matthew Fox , Hans Prozesky , Karl Technau , Shobna Sawry , Constance A Benson , Ronald J Bosch , Gregory D Kirk , Stephen Boswell , Kenneth H Mayer , Chris Grasso , Robert S Hogg , P Richard Harrigan , Julio S G Montaner , Benita Yip , Julia Zhu , Kate Salters , Karyn Gabler , Kate Buchacz , John T Brooks , Kelly A Gebo , Richard D Moore , Richard D Moore , Benigno Rodriguez , Michael A Horberg , Michael J Silverberg , Jennifer E Thorne , Charles Rabkin , Joseph B Margolick , Lisa P Jacobson , Gypsyamber D’souza , Marina B Klein , Sean B Rourke , Anita R Rachlis , Patrick Cupido , Robert F Hunter-Mellado , Angel M Mayor , M John Gill , Steven G Deeks , Jeffrey N Martin , Pragna Patel , John T Brooks , Michael S Saag , Michael J Mugavero , James Willig , Joseph J Eron , Sonia Napravnik , Mari M Kitahata , Heidi M Crane , Daniel R Drozd , Timothy R Sterling , David Haas , Peter Rebeiro , Megan Turner , Sally Bebawy , Ben Rogers , Amy C Justice , Robert Dubrow , David Fiellin , Stephen J Gange , Kathryn Anastos , Richard D Moore , Michael S Saag , Stephen J Gange , Mari M Kitahata , Keri N Althoff , Michael A Horberg , Marina B Klein , Rosemary G Mckaig , Aimee M Freeman , Richard D Moore , Aimee M Freeman , Carol Lent , Mari M Kitahata , Stephen E van Rompaey , Heidi M Crane , Daniel R Drozd , Liz Morton , Justin Mcreynolds , William B Lober , Stephen J Gange , Keri N Althoff , Alison G Abraham , Bryan Lau , Jinbing Zhang , Jerry Jing , Sharada Modur , Cherise Wong , Brenna Hogan , Fidel Desir , Bin Liu , Bin You , Pedro Cahn , Carina Cesar , Valeria Fink , Omar Sued , Emanuel Dell’isola , Hector Perez , Jose Valiente , Cleyton Yamamoto , Beatriz Grinsztejn , Valdilea Veloso , Paula Luz , Raquel de Boni , Sandra Cardoso Wagner , Ruth Friedman , Ronaldo Moreira , Jorge Pinto , Flavia Ferreira , Marcelle Maia , Regina Célia de Menezes Succi , Daisy Maria Machado , Aida de Fátima Barbosa Gouvêa , Marcelo Wolff , Claudia Cortes , Maria Fernanda Rodriguez , Gladys Allendes , Jean William Pape , Vanessa Rouzier , Adias Marcelin , Christian Perodin , Marco Tulio Luque , Denis Padgett , Juan Sierra Madero , Brenda Crabtree Ramirez , Paco Belaunzaran , Yanink Caro Vega , Eduardo Gotuzzo , Fernando Mejia , Gabriela Carriquiry , Catherine C Mcgowan , Bryan E Shepherd , Timothy R Sterling , Karu Jayathilake , Anna K Person , Peter Rebeiro , Mark Giganti , Jessica Castilho , Stephany N Duda , Fernanda Maruri , Hilary Vansell , P S Ly , V Khol , F J Zhang , H X Zhao , N Han , M P Lee , P C K Li , W Lam , Y T Chan , N Kumarasamy , S Saghayam , C Ezhilarasi , S Pujari , K Joshi , S Gaikwad , A Chitalikar , T P Merati , D N Wirawan , F Yuliana , E Yunihastuti , D Imran , A Widhani , J Tanuma , S Oka , T Nishijima , S Na , J Y Choi , J M Kim , B L H Sim , Y M Gani , R David , A Kamarulzaman , S F Syed Omar , S Ponnampalavanar , I Azwa , R Ditangco , E Uy , R Bantique , W W Wong , W W Ku , P C Wu , O T Ng , P L Lim , L S Lee , P S Ohnmar , A Avihingsanon , S Gatechompol , P Phanuphak , C Phadungphon , S Kiertiburanakul , S Sungkanuparph , L Chumla , N Sanmeema , R Chaiwarith , T Sirisanthana , W Kotarathititum , J Praparattanapan , P Kantipong , P Kambua , W Ratanasuwan , R Sriondee , K V Nguyen , H V Bui , D T H Nguyen , D T H Nguyen , D D Cuong , N V An , N T Luan , A H Sohn , J L Ross , B Petersen , D A Cooper , M G Law , A Jiamsakul , D C Boettiger , D Ellis , M Bloch , S Agrawal , T Vincent , D Allen , D Smith , A Rankin , D Baker , D J Templeton , C C O’connor , O Thackeray , E Jackson , K Mccallum , N Ryder , G Sweeney , D A Cooper , A Carr , K Macrae , K Hesse , R Finlayson , S Gupta , J Langton-Lockton , J Shakeshaft , K Brown , S Idle , N Arvela , R Varma , H Lu , D Couldwell , S Eswarappa , D Smith , V Furner , D Smith , G Cabrera , S Fernando , A Cogle , C Lawrence , B Mulhall , M Boyd , M G Law , K Petoumenos , R Puhr , R Huang , A Han , M Gunathilake , R Payne , M O’sullivan , A Croydon , D Russell , C Cashman , C Roberts , D Sowden , K Taing , P Marshall , D Orth , D Youds , D Rowling , N Latch , E Warzywoda , B Dickson , W Donohue , Richard D Moore , S Edwards , S Boyd , N J Roth , H Lau , T Read , J Silvers , W Zeng , J Hoy , K Watson , M Bryant , S Price , I Woolley , M Giles , T Korman , J Williams , D Nolan , A Allen , G Guelfi , G Mills , C Wharry , N Raymond , K Bargh , D J Templeton , M Giles , K Brown , J Hoy
Ali Judd
  • Function : Author
Robert Zangerle
  • Function : Author
Giota Touloumi
  • Function : Author
Josiane Warszawski
  • Function : Author
Laurence Meyer
François Dabis
  • Function : Author
Murielle Mary Krause
  • Function : Author
Jade Ghosn
  • Function : Author
Catherine Leport
  • Function : Author
Linda Wittkop
  • Function : Author
Peter Reiss
  • Function : Author
Ferdinand Wit
  • Function : Author
Maria Prins
  • Function : Author
Heiner Bucher
  • Function : Author
Diana Gibb
  • Function : Author
Gerd Fätkenheuer
  • Function : Author
del Amo Julia
  • Function : Author
Niels Obel
  • Function : Author
Claire Thorne
  • Function : Author
Amanda Mocroft
  • Function : Author
Ole Kirk
  • Function : Author
Christoph Stephan
  • Function : Author
Santiago Pérez-Hoyos
  • Function : Author
Osamah Hamouda
  • Function : Author
Barbara Bartmeyer
  • Function : Author
Nikoloz Chkhartishvili
  • Function : Author
Antoni Noguera-Julian
  • Function : Author
Andrea Antinori
  • Function : Author
Antonella D’arminio Monforte
  • Function : Author
Norbert Brockmeyer
  • Function : Author
Luis Prieto
  • Function : Author
Pablo Rojo Conejo
  • Function : Author
Antoni Soriano-Arandes
  • Function : Author
Manuel Battegay
  • Function : Author
Roger Kouyos
  • Function : Author
Cristina Mussini
  • Function : Author
Pat Tookey
  • Function : Author
Jordi Casabona
  • Function : Author
Jose M Miró
  • Function : Author
Antonella Castagna
  • Function : Author
Deborah Konopnick
  • Function : Author
Tessa Goetghebuer
  • Function : Author
Anders Sönnerborg
  • Function : Author
Eugenia Quiros-Roldan
  • Function : Author
Caroline Sabin
  • Function : Author
Ramon Teira
  • Function : Author
Myriam Garrido
  • Function : Author
David Haerry
  • Function : Author
Stéphane de Wit
  • Function : Author
Jose M Miró
  • Function : Author
Dominique Costagliola
  • Function : Author
Antonella D’arminio-Monforte
  • Function : Author
Antonella Castagna
  • Function : Author
Julia del Amo
  • Function : Author
Amanda Mocroft
  • Function : Author
Dorthe Raben
  • Function : Author
Geneviève Chêne
  • Function : Author
Ali Judd
  • Function : Author
Conejo Pablo Rojo
  • Function : Author
Diana Barger
  • Function : Author
Christine Schwimmer
  • Function : Author
Monique Termote
  • Function : Author
Linda Wittkop
  • Function : Author
Maria Campbell
  • Function : Author
Casper M Frederiksen
  • Function : Author
Nina Friis-Møller
  • Function : Author
Jesper Kjaer
  • Function : Author
Dorthe Raben
  • Function : Author
Rikke Salbøl Brandt
  • Function : Author
Juan Berenguer
  • Function : Author
Julia Bohlius
  • Function : Author
Vincent Bouteloup
  • Function : Author
Heiner Bucher
  • Function : Author
Alessandro Cozzi-Lepri
  • Function : Author
François Dabis
  • Function : Author
Antonella D’arminio Monforte
  • Function : Author
Mary-Anne Davies
  • Function : Author
Julia del Amo
  • Function : Author
Maria Dorrucci
  • Function : Author
David Dunn
  • Function : Author
Matthias Egger
  • Function : Author
Hansjakob Furrer
  • Function : Author
Marguerite Guiguet
  • Function : Author
Ali Judd
  • Function : Author
Ole Kirk
  • Function : Author
Olivier Lambotte
  • Function : Author
Valériane Leroy
Sara Lodi
  • Function : Author
Sophie Matheron
  • Function : Author
Laurence Meyer
  • Function : Author
Jose M Miró
  • Function : Author
Amanda Mocroft
  • Function : Author
Susana Monge
  • Function : Author
Fumiyo Nakagawa
  • Function : Author
Roger Paredes
  • Function : Author
Andrew Phillips
  • Function : Author
Massimo Puoti
  • Function : Author
Eliane Rohner
  • Function : Author
Michael Schomaker
  • Function : Author
Colette Smit
  • Function : Author
Jonathan Sterne
  • Function : Author
Rodolphe Thiebaut
  • Function : Author
Claire Thorne
  • Function : Author
Carlo Torti
  • Function : Author
Marc van der Valk
  • Function : Author
Linda Wittkop
  • Function : Author
Frank Tanser
  • Function : Author
Michael Vinikoor
  • Function : Author
Eusebio Macete
  • Function : Author
Robin Wood
  • Function : Author
Kathryn Stinson
  • Function : Author
Daniela Garone
  • Function : Author
Geoffrey Fatti
  • Function : Author
Janet Giddy
  • Function : Author
Kennedy Malisita
  • Function : Author
Brian Eley
  • Function : Author
Christiane Fritz
  • Function : Author
Michael Hobbins
  • Function : Author
Kamelia Kamenova
  • Function : Author
Matthew Fox
  • Function : Author
Hans Prozesky
  • Function : Author
Karl Technau
  • Function : Author
Shobna Sawry
  • Function : Author
Constance A Benson
  • Function : Author
Ronald J Bosch
  • Function : Author
Gregory D Kirk
  • Function : Author
Stephen Boswell
  • Function : Author
Kenneth H Mayer
  • Function : Author
Chris Grasso
  • Function : Author
Robert S Hogg
  • Function : Author
P Richard Harrigan
  • Function : Author
Julio S G Montaner
  • Function : Author
Benita Yip
  • Function : Author
Julia Zhu
  • Function : Author
Kate Salters
  • Function : Author
Karyn Gabler
  • Function : Author
Kate Buchacz
  • Function : Author
John T Brooks
  • Function : Author
Kelly A Gebo
  • Function : Author
Richard D Moore
  • Function : Author
Richard D Moore
  • Function : Author
Benigno Rodriguez
  • Function : Author
Michael A Horberg
  • Function : Author
Michael J Silverberg
  • Function : Author
Jennifer E Thorne
  • Function : Author
Charles Rabkin
  • Function : Author
Joseph B Margolick
  • Function : Author
Lisa P Jacobson
  • Function : Author
Gypsyamber D’souza
  • Function : Author
Marina B Klein
  • Function : Author
Sean B Rourke
  • Function : Author
Anita R Rachlis
  • Function : Author
Patrick Cupido
  • Function : Author
Robert F Hunter-Mellado
  • Function : Author
Angel M Mayor
  • Function : Author
M John Gill
  • Function : Author
Steven G Deeks
  • Function : Author
Jeffrey N Martin
  • Function : Author
Pragna Patel
  • Function : Author
John T Brooks
  • Function : Author
Michael S Saag
  • Function : Author
Michael J Mugavero
  • Function : Author
James Willig
  • Function : Author
Joseph J Eron
  • Function : Author
Sonia Napravnik
  • Function : Author
Mari M Kitahata
  • Function : Author
Heidi M Crane
  • Function : Author
Daniel R Drozd
  • Function : Author
Timothy R Sterling
  • Function : Author
David Haas
  • Function : Author
Peter Rebeiro
  • Function : Author
Megan Turner
  • Function : Author
Sally Bebawy
  • Function : Author
Ben Rogers
  • Function : Author
Amy C Justice
  • Function : Author
Robert Dubrow
  • Function : Author
David Fiellin
  • Function : Author
Stephen J Gange
  • Function : Author
Kathryn Anastos
  • Function : Author
Richard D Moore
  • Function : Author
Michael S Saag
  • Function : Author
Stephen J Gange
  • Function : Author
Mari M Kitahata
  • Function : Author
Keri N Althoff
  • Function : Author
Michael A Horberg
  • Function : Author
Marina B Klein
  • Function : Author
Rosemary G Mckaig
  • Function : Author
Aimee M Freeman
  • Function : Author
Richard D Moore
  • Function : Author
Aimee M Freeman
  • Function : Author
Carol Lent
  • Function : Author
Mari M Kitahata
  • Function : Author
Stephen E van Rompaey
  • Function : Author
Heidi M Crane
  • Function : Author
Daniel R Drozd
  • Function : Author
Liz Morton
  • Function : Author
Justin Mcreynolds
  • Function : Author
William B Lober
  • Function : Author
Stephen J Gange
  • Function : Author
Keri N Althoff
  • Function : Author
Alison G Abraham
  • Function : Author
Bryan Lau
  • Function : Author
Jinbing Zhang
  • Function : Author
Jerry Jing
  • Function : Author
Sharada Modur
  • Function : Author
Cherise Wong
  • Function : Author
Brenna Hogan
  • Function : Author
Fidel Desir
  • Function : Author
Bin Liu
  • Function : Author
Bin You
  • Function : Author
Pedro Cahn
  • Function : Author
Carina Cesar
  • Function : Author
Valeria Fink
  • Function : Author
Omar Sued
  • Function : Author
Emanuel Dell’isola
  • Function : Author
Hector Perez
  • Function : Author
Jose Valiente
  • Function : Author
Cleyton Yamamoto
  • Function : Author
Beatriz Grinsztejn
  • Function : Author
Valdilea Veloso
  • Function : Author
Paula Luz
  • Function : Author
Raquel de Boni
  • Function : Author
Sandra Cardoso Wagner
  • Function : Author
Ruth Friedman
  • Function : Author
Ronaldo Moreira
  • Function : Author
Jorge Pinto
  • Function : Author
Flavia Ferreira
  • Function : Author
Marcelle Maia
  • Function : Author
Regina Célia de Menezes Succi
  • Function : Author
Daisy Maria Machado
  • Function : Author
Marcelo Wolff
  • Function : Author
Claudia Cortes
  • Function : Author
Maria Fernanda Rodriguez
  • Function : Author
Gladys Allendes
  • Function : Author
Jean William Pape
  • Function : Author
Vanessa Rouzier
  • Function : Author
Adias Marcelin
  • Function : Author
Christian Perodin
  • Function : Author
Marco Tulio Luque
  • Function : Author
Denis Padgett
  • Function : Author
Juan Sierra Madero
  • Function : Author
Brenda Crabtree Ramirez
  • Function : Author
Paco Belaunzaran
  • Function : Author
Yanink Caro Vega
  • Function : Author
Eduardo Gotuzzo
  • Function : Author
Fernando Mejia
  • Function : Author
Gabriela Carriquiry
  • Function : Author
Catherine C Mcgowan
  • Function : Author
Bryan E Shepherd
  • Function : Author
Timothy R Sterling
  • Function : Author
Karu Jayathilake
  • Function : Author
Anna K Person
  • Function : Author
Peter Rebeiro
  • Function : Author
Mark Giganti
  • Function : Author
Jessica Castilho
  • Function : Author
Stephany N Duda
  • Function : Author
Fernanda Maruri
  • Function : Author
Hilary Vansell
  • Function : Author
P S Ly
  • Function : Author
V Khol
  • Function : Author
F J Zhang
  • Function : Author
H X Zhao
  • Function : Author
N Han
  • Function : Author
M P Lee
  • Function : Author
P C K Li
  • Function : Author
W Lam
  • Function : Author
Y T Chan
  • Function : Author
N Kumarasamy
  • Function : Author
S Saghayam
  • Function : Author
C Ezhilarasi
  • Function : Author
S Pujari
  • Function : Author
K Joshi
  • Function : Author
S Gaikwad
  • Function : Author
A Chitalikar
  • Function : Author
T P Merati
  • Function : Author
D N Wirawan
  • Function : Author
F Yuliana
  • Function : Author
E Yunihastuti
  • Function : Author
D Imran
  • Function : Author
A Widhani
  • Function : Author
J Tanuma
  • Function : Author
S Oka
  • Function : Author
T Nishijima
  • Function : Author
S Na
  • Function : Author
J Y Choi
  • Function : Author
J M Kim
  • Function : Author
B L H Sim
  • Function : Author
Y M Gani
  • Function : Author
R David
  • Function : Author
A Kamarulzaman
  • Function : Author
S F Syed Omar
  • Function : Author
S Ponnampalavanar
  • Function : Author
I Azwa
  • Function : Author
R Ditangco
  • Function : Author
E Uy
  • Function : Author
R Bantique
  • Function : Author
W W Wong
  • Function : Author
W W Ku
  • Function : Author
P C Wu
  • Function : Author
O T Ng
  • Function : Author
P L Lim
  • Function : Author
L S Lee
  • Function : Author
P S Ohnmar
  • Function : Author
A Avihingsanon
  • Function : Author
S Gatechompol
  • Function : Author
P Phanuphak
  • Function : Author
C Phadungphon
  • Function : Author
S Kiertiburanakul
  • Function : Author
S Sungkanuparph
  • Function : Author
L Chumla
  • Function : Author
N Sanmeema
  • Function : Author
R Chaiwarith
  • Function : Author
T Sirisanthana
  • Function : Author
W Kotarathititum
  • Function : Author
J Praparattanapan
  • Function : Author
P Kantipong
  • Function : Author
P Kambua
  • Function : Author
W Ratanasuwan
  • Function : Author
R Sriondee
  • Function : Author
K V Nguyen
  • Function : Author
H V Bui
  • Function : Author
D T H Nguyen
  • Function : Author
D T H Nguyen
  • Function : Author
D D Cuong
  • Function : Author
N V An
  • Function : Author
N T Luan
  • Function : Author
A H Sohn
  • Function : Author
J L Ross
  • Function : Author
B Petersen
  • Function : Author
D A Cooper
  • Function : Author
M G Law
  • Function : Author
A Jiamsakul
  • Function : Author
D C Boettiger
  • Function : Author
D Ellis
  • Function : Author
M Bloch
  • Function : Author
S Agrawal
  • Function : Author
T Vincent
  • Function : Author
D Allen
  • Function : Author
D Smith
  • Function : Author
A Rankin
  • Function : Author
D Baker
  • Function : Author
D J Templeton
  • Function : Author
C C O’connor
  • Function : Author
O Thackeray
  • Function : Author
E Jackson
  • Function : Author
K Mccallum
  • Function : Author
N Ryder
  • Function : Author
G Sweeney
  • Function : Author
D A Cooper
  • Function : Author
A Carr
  • Function : Author
K Macrae
  • Function : Author
K Hesse
  • Function : Author
R Finlayson
  • Function : Author
S Gupta
  • Function : Author
J Langton-Lockton
  • Function : Author
J Shakeshaft
  • Function : Author
K Brown
  • Function : Author
S Idle
  • Function : Author
N Arvela
  • Function : Author
R Varma
  • Function : Author
H Lu
  • Function : Author
D Couldwell
  • Function : Author
S Eswarappa
  • Function : Author
D Smith
  • Function : Author
V Furner
  • Function : Author
D Smith
  • Function : Author
G Cabrera
  • Function : Author
S Fernando
  • Function : Author
A Cogle
  • Function : Author
C Lawrence
  • Function : Author
B Mulhall
  • Function : Author
M Boyd
  • Function : Author
M G Law
  • Function : Author
K Petoumenos
  • Function : Author
R Puhr
  • Function : Author
R Huang
  • Function : Author
A Han
  • Function : Author
M Gunathilake
  • Function : Author
R Payne
  • Function : Author
M O’sullivan
  • Function : Author
A Croydon
  • Function : Author
D Russell
  • Function : Author
C Cashman
  • Function : Author
C Roberts
  • Function : Author
D Sowden
  • Function : Author
K Taing
  • Function : Author
P Marshall
  • Function : Author
D Orth
  • Function : Author
D Youds
  • Function : Author
D Rowling
  • Function : Author
N Latch
  • Function : Author
E Warzywoda
  • Function : Author
B Dickson
  • Function : Author
W Donohue
  • Function : Author
Richard D Moore
  • Function : Author
S Edwards
  • Function : Author
S Boyd
  • Function : Author
N J Roth
  • Function : Author
H Lau
  • Function : Author
T Read
  • Function : Author
J Silvers
  • Function : Author
W Zeng
  • Function : Author
J Hoy
  • Function : Author
K Watson
  • Function : Author
M Bryant
  • Function : Author
S Price
  • Function : Author
I Woolley
  • Function : Author
M Giles
  • Function : Author
T Korman
  • Function : Author
J Williams
  • Function : Author
D Nolan
  • Function : Author
A Allen
  • Function : Author
G Guelfi
  • Function : Author
G Mills
  • Function : Author
C Wharry
  • Function : Author
N Raymond
  • Function : Author
K Bargh
  • Function : Author
D J Templeton
  • Function : Author
M Giles
  • Function : Author
K Brown
  • Function : Author
J Hoy
  • Function : Author

Abstract

Background. We compared Kaposi sarcoma (KS) risk in adults who started antiretroviral therapy (ART) across the Asia-Pacific, South Africa, Europe, Latin, and North America. Methods. We included cohort data of human immunodeficiency virus (HIV)-positive adults who started ART after 1995 within the framework of 2 large collaborations of observational HIV cohorts. We present incidence rates and adjusted hazard ratios (aHRs). Results. We included 208 140 patients from 57 countries. Over a period of 1 066 572 person-years, 2046 KS cases were diagnosed. KS incidence rates per 100 000 person-years were 52 in the Asia-Pacific and ranged between 180 and 280 in the other regions. KS risk was 5 times higher in South African women (aHR, 4.56; 95% confidence intervals [CI], 2.73-7.62) than in their European counterparts, and 2 times higher in South African men (2.21; 1.34-3.63). In Europe, Latin, and North America KS risk was 6 times higher in men who have sex with men (aHR, 5.95; 95% CI, 5.09-6.96) than in women. Comparing patients with current CD4 cell counts ≥700 cells/µL with those whose counts were <50 cells/µL, the KS risk was halved in South Africa (aHR, 0.53; 95% CI, .17-1.63) but reduced by ≥95% in other regions. Conclusions. Despite important ART-related declines in KS incidence, men and women in South Africa and men who have sex with men remain at increased KS risk, likely due to high human herpesvirus 8 coinfection rates. Early ART initiation and maintenance of high CD4 cell counts are essential to further reducing KS incidence worldwide, but additional measures might be needed, especially in Southern Africa.

Dates and versions

hal-03708308 , version 1 (29-06-2022)

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Ali Judd, Robert Zangerle, Giota Touloumi, Josiane Warszawski, Laurence Meyer, et al.. Comparison of Kaposi Sarcoma Risk in Human Immunodeficiency Virus-Positive Adults Across 5 Continents: A Multiregional Multicohort Study. Clinical Infectious Diseases, 2017, 65 (8), pp.1316-1326. ⟨10.1093/cid/cix480⟩. ⟨hal-03708308⟩
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