Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases - Sorbonne Université Access content directly
Journal Articles Kidney International Year : 2021

Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases

1 OSU - Ohio State University [Columbus]
2 LA BioMed - Los Angeles Biomedical Research Institute
3 University of Leicester
4 CRIBL - Contrôle de la Réponse Immune B et des Lymphoproliférations
5 CHU de Poitiers [La Milétrie] - Centre hospitalier universitaire de Poitiers = Poitiers University Hospital
6 Mass General Brigham-Salem Hospital
7 HKU - The University of Hong Kong
8 Imperial College London
9 Mayo Clinic [Rochester]
10 UNC - University of North Carolina [Chapel Hill]
11 David Geffen School of Medicine [Los Angeles]
12 CAM - University of Cambridge [UK]
13 The George Institute for Global Health India
14 Manipal Academy of Higher Education
15 Mount Elizabeth Novena Hospital
16 NJU - Nanjing University
17 Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán - National Institute of Medical Science and Nutrition Salvador Zubiran [Mexico]
18 University of Iowa [Iowa City]
19 CUMC - Columbia University Medical Center
20 Ohio Kidney Associates
21 University of Toronto
22 Des Maladies Rénales Rares aux Maladies Fréquentes, Remodelage et Réparation
23 Centre Hospitalier Le Mans (CH Le Mans)
24 University of Groningen [Groningen]
25 Juntendo University Hospital [Tokyo]
26 UK - Univerzita Karlova [Praha, Česká republika] = Charles University [Prague, Czech Republic]
27 IRCCS Ospedale Pediatrico Bambino Gesù = Bambino Gesù Children’s Hospital
28 Radboud University Medical Center [Nijmegen]
29 McMaster University [Hamilton, Ontario]
30 Flinders University [Adelaide, Australia]
31 The University of Sydney
32 University of Calgary
34 UKA - Universitätsklinikum RWTH Aachen - University Hospital Aachen [Aachen, Germany]
Zhi-Hong Liu
  • Function : Author
Michael Cheung
  • Function : Author
Amy Earley
  • Function : Author


The Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for the Management of Glomerular Diseases is an update to the KDIGO 2012 guideline. The aim is to assist clinicians caring for individuals with glomerulonephritis (GN), both adults and children. The scope includes various glomerular diseases, including IgA nephropathy and IgA vasculitis, membranous nephropathy, nephrotic syndrome, minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), infection-related GN, antineutrophil cytoplasmic antibody (ANCA) vasculitis, lupus nephritis, and anti–glomerular basement membrane antibody GN. In addition, this guideline will be the first to address the subtype of complement-mediated diseases. Each chapter follows the same format providing guidance related to diagnosis, prognosis, treatment, and special situations. The goal of the guideline is to generate a useful resource for clinicians and patients by providing actionable recommendations based on evidence syntheses, with useful infographics incorporating views from experts in the field. Another aim is to propose research recommendations for areas where there are gaps in knowledge. The guideline targets a broad global audience of clinicians treating GN while being mindful of implications for policy and cost. Development of this guideline update followed an explicit process whereby treatment approaches and guideline recommendations are based on systematic reviews of relevant studies, and appraisal of the quality of the evidence and the strength of recommendations followed the “Grading of Recommendations Assessment, Development and Evaluation” (GRADE) approach. Limitations of the evidence are discussed, with areas of future research also presented.
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Dates and versions

hal-03915859 , version 1 (27-09-2023)



Brad Rovin, Sharon Adler, Jonathan Barratt, Frank Bridoux, Kelly Burdge, et al.. Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases. Kidney International, 2021, 100 (4), pp.753-779. ⟨10.1016/j.kint.2021.05.015⟩. ⟨hal-03915859⟩
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