ATP-binding cassette transporters expression in rats with cirrhosis and hepatic encephalopathy - Sorbonne Université
Article Dans Une Revue Clinics and Research in Hepatology and Gastroenterology Année : 2022

ATP-binding cassette transporters expression in rats with cirrhosis and hepatic encephalopathy

Charlotte Bouzbib
  • Fonction : Auteur
Haquima El Mourabit
  • Fonction : Auteur
Elisabeth Lasnier
  • Fonction : Auteur
Sarah Mouri
  • Fonction : Auteur
Chantal Housset
Dominique Thabut
  • Fonction : Auteur
  • PersonId : 1081430
Nicolas Weiss
Marika Rudler
  • Fonction : Auteur

Résumé

Background: Pathophysiology of acute encephalopathy in cirrhotic patients is not completely understood. Factors implicated include ammonia, inflammation, various metabolic disorders and drug toxicity. Recent studies have evidenced an increased permeability of the blood-brain barrier (BBB) in models of chronic liver disease and encephalopathy, either to solutes, or to leukocytes. A modification of the expression of BBB ATP-Binding Cassette (ABC) transporters, actively transporting endogenous and exogenous components through the BBB, has been

Dates et versions

hal-03972206 , version 1 (15-03-2023)

Identifiants

Citer

Charlotte Bouzbib, Haquima El Mourabit, Dominique Wendum, Elisabeth Lasnier, Sarah Mouri, et al.. ATP-binding cassette transporters expression in rats with cirrhosis and hepatic encephalopathy. Clinics and Research in Hepatology and Gastroenterology, 2022, 46 (9), pp.101784. ⟨10.1016/j.clinre.2021.101784⟩. ⟨hal-03972206⟩
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