miR-1224 Acute liver failure Cell death Proliferation Biomarker Nfib Oxidative stress miR-1224 Acute liver failure Cell death Proliferation Biomarker Nfib Oxidative stress miR-1224, acute liver failure, cell death, proliferation, biomarker, Nfib, oxidative stress ALF, Acute liver failure I/R, Ischemia-reperfusion miRNA, microRNA APAP, acetaminophen H 2 O 2 , Hydrogen peroxide CCl 4 , Carbon tetrachloride BrdU, 5-bromo-2'-deoxyuridine AUC, Area under curve SR, spontaneous recovery NSR, non- spontaneous recovery siRNA, small interfering RNA mRNA, messenger RNA qRT-PCR, quantitative real-time polymerase chain reaction AU, arbritary units H/R, hypoxia/regeneration TNF, tumor necrosis factor MTT, methyl thiazol tetrazolium cl. CASP-3, cleaved Caspase-3 GAPDH, glyceraldehyde-3-phosphate dehydrogenase UTR, untranslated region TUNEL, terminal deoxynucleotide transferase nick end labeling ROS, reactive oxygen species miR-1224, acute liver failure, cell death, proliferation, biomarker, Nfib, oxidative stress ALF, Acute liver failure I/R, Ischemia-reperfusion miRNA, microRNA APAP, acetaminophen H 2 O 2 , Hydrogen peroxide CCl 4 , Carbon tetrachloride BrdU, 5-bromo-2'-deoxyuridine AUC, Area under curve SR, spontaneous recovery NSR, non- spontaneous recovery siRNA, small interfering RNA mRNA, messenger RNA qRT-PCR, quantitative real-time polymerase chain reaction AU, arbritary units H/R, hypoxia/regeneration TNF, tumor necrosis factor MTT, methyl thiazol tetrazolium cl. CASP-3, cleaved Caspase-3 GAPDH, glyceraldehyde-3-phosphate dehydrogenase UTR, untranslated region TUNEL, terminal deoxynucleotide transferase nick end labeling ROS, reactive oxygen species