miR-1224 inhibits cell proliferation in acute liver failure by targeting the antiapoptotic gene Nfib - Sorbonne Université
Article Dans Une Revue Journal of Hepatology Année : 2017

miR-1224 inhibits cell proliferation in acute liver failure by targeting the antiapoptotic gene Nfib

Mots clés

miR-1224 Acute liver failure Cell death Proliferation Biomarker Nfib Oxidative stress miR-1224 Acute liver failure Cell death Proliferation Biomarker Nfib Oxidative stress miR-1224, acute liver failure, cell death, proliferation, biomarker, Nfib, oxidative stress ALF, Acute liver failure I/R, Ischemia-reperfusion miRNA, microRNA APAP, acetaminophen H 2 O 2 , Hydrogen peroxide CCl 4 , Carbon tetrachloride BrdU, 5-bromo-2'-deoxyuridine AUC, Area under curve SR, spontaneous recovery NSR, non- spontaneous recovery siRNA, small interfering RNA mRNA, messenger RNA qRT-PCR, quantitative real-time polymerase chain reaction AU, arbritary units H/R, hypoxia/regeneration TNF, tumor necrosis factor MTT, methyl thiazol tetrazolium cl. CASP-3, cleaved Caspase-3 GAPDH, glyceraldehyde-3-phosphate dehydrogenase UTR, untranslated region TUNEL, terminal deoxynucleotide transferase nick end labeling ROS, reactive oxygen species miR-1224, acute liver failure, cell death, proliferation, biomarker, Nfib, oxidative stress ALF, Acute liver failure I/R, Ischemia-reperfusion miRNA, microRNA APAP, acetaminophen H 2 O 2 , Hydrogen peroxide CCl 4 , Carbon tetrachloride BrdU, 5-bromo-2'-deoxyuridine AUC, Area under curve SR, spontaneous recovery NSR, non- spontaneous recovery siRNA, small interfering RNA mRNA, messenger RNA qRT-PCR, quantitative real-time polymerase chain reaction AU, arbritary units H/R, hypoxia/regeneration TNF, tumor necrosis factor MTT, methyl thiazol tetrazolium cl. CASP-3, cleaved Caspase-3 GAPDH, glyceraldehyde-3-phosphate dehydrogenase UTR, untranslated region TUNEL, terminal deoxynucleotide transferase nick end labeling ROS, reactive oxygen species
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hal-03976518 , version 1 (21-02-2023)

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Sanchari Roy, Heike Bantel, Franziska Wandrer, Anne Theres Schneider, Jérémie Gautheron, et al.. miR-1224 inhibits cell proliferation in acute liver failure by targeting the antiapoptotic gene Nfib. Journal of Hepatology, 2017, 67, pp.966 - 978. ⟨10.1016/j.jhep.2017.06.007⟩. ⟨hal-03976518⟩
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