Deciphering pathological remodelling of the human cartilage extracellular matrix in osteoarthritis at the supramolecular level - Sorbonne Université
Journal Articles Nanoscale Year : 2022

Deciphering pathological remodelling of the human cartilage extracellular matrix in osteoarthritis at the supramolecular level

Abstract

Osteoarthritis induces a combination of chemical, structural and nanomechanical changes to collagen fibrils and aggrecan aggregates, the main building blocks of cartilage ECM, that may be mimicked by specific enzymatic reactions.
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hal-03986333 , version 1 (13-02-2023)

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Ilhem Lilia Jaabar, Pauline Cornette, Antoine Miche, Kristell Wanherdrick, Vincent Dupres, et al.. Deciphering pathological remodelling of the human cartilage extracellular matrix in osteoarthritis at the supramolecular level. Nanoscale, 2022, 14 (24), pp.8691-8708. ⟨10.1039/d2nr00474g⟩. ⟨hal-03986333⟩
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