Reorganisation of faecal microbiota transplant services during the COVID-19 pandemic
Gianluca Ianiro
(1)
,
Benjamin Mullish
(2)
,
Colleen Kelly
(3)
,
Zain Kassam
(4)
,
Ed Kuijper
(5)
,
Siew Ng
(6)
,
Tariq Iqbal
(7, 8)
,
Jessica Allegretti
(9)
,
Stefano Bibbò
(1)
,
Harry Sokol
(10, 11, 12)
,
Faming Zhang
(13)
,
Monika Fischer
(14)
,
Samuel Paul Costello
(15)
,
Josbert Keller
(5, 16)
,
Luca Masucci
(1)
,
Joffrey van Prehn
(5)
,
Gianluca Quaranta
(1)
,
Mohammed Nabil Quraishi
(7, 8)
,
Jonathan Segal
(17)
,
Dina Kao
(18)
,
Reetta Satokari
(19)
,
Maurizio Sanguinetti
(1)
,
Herbert Tilg
(20)
,
Antonio Gasbarrini
(1)
,
Giovanni Cammarota
(1)
1
Unicatt -
Università cattolica del Sacro Cuore = Catholic University of the Sacred Heart [Roma]
2 Imperial College London
3 Brown University
4 Finch Therapeutics Group
5 LUMC - Leiden University Medical Center
6 CUHK - The Chinese University of Hong Kong [Hong Kong]
7 University of Birmingham [Birmingham]
8 University Hospitals Birmingham [Birmingham, Royaume-Uni]
9 HMS - Harvard Medical School [Boston]
10 CRSA - Centre de Recherche Saint-Antoine
11 CHU Saint-Antoine [AP-HP]
12 MICALIS - MICrobiologie de l'ALImentation au Service de la Santé
13 Nanjing Medical University
14 IUPUI - Indiana University - Purdue University Indianapolis
15 University of Adelaide
16 HMC - Haaglanden Medisch Centrum [Nederland] = Haaglanden Medical Center [Netherlands]
17 St Mark's Hospital
18 University of Alberta
19 Helsingin yliopisto = Helsingfors universitet = University of Helsinki
20 IMU - Innsbruck Medical University = Medizinische Universität Innsbruck
2 Imperial College London
3 Brown University
4 Finch Therapeutics Group
5 LUMC - Leiden University Medical Center
6 CUHK - The Chinese University of Hong Kong [Hong Kong]
7 University of Birmingham [Birmingham]
8 University Hospitals Birmingham [Birmingham, Royaume-Uni]
9 HMS - Harvard Medical School [Boston]
10 CRSA - Centre de Recherche Saint-Antoine
11 CHU Saint-Antoine [AP-HP]
12 MICALIS - MICrobiologie de l'ALImentation au Service de la Santé
13 Nanjing Medical University
14 IUPUI - Indiana University - Purdue University Indianapolis
15 University of Adelaide
16 HMC - Haaglanden Medisch Centrum [Nederland] = Haaglanden Medical Center [Netherlands]
17 St Mark's Hospital
18 University of Alberta
19 Helsingin yliopisto = Helsingfors universitet = University of Helsinki
20 IMU - Innsbruck Medical University = Medizinische Universität Innsbruck
Gianluca Ianiro
- Function : Author
- PersonId : 1231817
- ORCID : 0000-0002-8318-0515
Benjamin Mullish
- Function : Author
- PersonId : 1231818
- ORCID : 0000-0001-6300-3100
Siew Ng
- Function : Author
- PersonId : 800088
- ORCID : 0000-0002-6850-4454
Mohammed Nabil Quraishi
- Function : Author
- PersonId : 1231819
- ORCID : 0000-0003-2338-8397
Herbert Tilg
- Function : Author
- PersonId : 1231821
- ORCID : 0000-0002-4235-2579
Giovanni Cammarota
- Function : Author
- PersonId : 1231822
- ORCID : 0000-0002-3626-6148
Abstract
The COVID-19 pandemic has led to an exponential increase in SARS-CoV-2 infections and associated deaths, and represents a significant challenge to healthcare professionals and facilities. Individual countries have taken several prevention and containment actions to control the spread of infection, including measures to guarantee safety of both healthcare professionals and patients who are at increased risk of infection from COVID-19. Faecal microbiota transplantation (FMT) has a well-established role in the treatment of Clostridioides difficile infection. In the time of the pandemic, FMT centres and stool banks are required to adopt a workflow that continues to ensure reliable patient access to FMT while maintaining safety and quality of procedures. In this position paper, based on the best available evidence, worldwide FMT experts provide guidance on issues relating to the impact of COVID-19 on FMT, including patient selection, donor recruitment and selection, stool manufacturing, FMT procedures, patient follow-up and research activities.