Extensive head and neck skin cancers: Carcinologic surgery as a cornerstone of treatment - Sorbonne Université Access content directly
Journal Articles Journal of Stomatology, Oral and Maxillofacial Surgery Year : 2024

Extensive head and neck skin cancers: Carcinologic surgery as a cornerstone of treatment

Thomas Bondi
  • Function : Author
André Chaine
  • Function : Author
Jean-Philippe Foy
  • Function : Author
Mourad Benassarou
  • Function : Author
Chloé Bertolus
  • Function : Author


Background and Objective. The prevalence of extensive skin cancers increases with the aging of the population. Surgical management is the gold standard of curative treatment while morbidity is not negligible. There are few data in the literature concerning extensive head and neck cutaneous cancers. The aim of this article is to report our experience of curative management of head and neck extensive skin cancers. Method. In this single-center retrospective observational study, we report a series of 17 patients with extensive skin facial cancers treated by surgery between 2013 and 2022 in the maxillofacial surgery department of the Pitié-Salpêtrière Hospital. We collected clinical, therapeutic, histological, and carcinologic data. Results. The median age of the patients was 66 years [35-94]. There were 9 male and 8 women. Scalp (39%) and cheek (22%) locations were the most frequent ones. The most frequent histological types were squamous cell carcinoma (61%) and basal cell carcinoma (17%). Three patients received neoadjuvant treatment. The surgical treatment consisted mainly of carcinological resection followed by one-stage reconstruction by free flap for 5 (30%) patients and without reconstruction for primary for 12 (70%) patients, of whom 8 benefited from secondary reconstruction. Five patients received adjuvant radiotherapy or radio-chemotherapy. With a median follow-up of 40 months (2-72), the median overall survival was 40 months (12-72). Conclusion. We know that extensive skin cancers of the face have a good prognosis on condition that the carcinological and reconstructive requirements are respected. Surgery remains the cornerstone of treatment while the improvement of adjuvant therapies, in particular the rise of immunotherapies or other targeted therapies, may allow to limit recurrences.
Fichier principal
Vignette du fichier
20231210_Manuscript_Facial_Extensive_Cancers_JB_clean.pdf (6.2 Mo) Télécharger le fichier
Origin Files produced by the author(s)

Dates and versions

hal-04357889 , version 1 (21-12-2023)



Thomas Bondi, André Chaine, Jean-Philippe Foy, Mourad Benassarou, Chloé Bertolus, et al.. Extensive head and neck skin cancers: Carcinologic surgery as a cornerstone of treatment. Journal of Stomatology, Oral and Maxillofacial Surgery, 2024, 125 (4), pp.101737. ⟨10.1016/j.jormas.2023.101737⟩. ⟨hal-04357889⟩
7 View
8 Download



Gmail Mastodon Facebook X LinkedIn More