Disentangling clinical and biological trajectories of neurodegenerative diseases - Sorbonne Université
Journal Articles Nature Reviews Neurology Year : 2024

Disentangling clinical and biological trajectories of neurodegenerative diseases

Abstract

In recent years, we have seen a shift towards defining sporadic neurodegenerative diseases as a biological continuum. Here, we discuss the risks associated with this shift, emphasize the importance of maintaining a strong connection between disease definitions and subsequent clinical outcomes, and suggest clinicobiological frameworks to disentangle multiple discrete nosological entities.
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Saturday, February 8, 2025
Embargoed file
Saturday, February 8, 2025
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Dates and versions

hal-04679023 , version 1 (28-08-2024)

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Nicolas Villain, Vincent Planche. Disentangling clinical and biological trajectories of neurodegenerative diseases. Nature Reviews Neurology, 2024, ⟨10.1038/s41582-024-01004-3⟩. ⟨hal-04679023⟩
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