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Intérêt de la nutrition préopératoire en chirurgie digestive pour des patients sévèrement dénutris : étude rétrospective.

Abstract : Introduction: Malnutrition increases postoperative morbidity and mortality. The objective of this study was to evaluate preoperative refeeding in malnourished patients at risk of refeeding syndrome (RS). Methodology: A retrospective study, conducted between June 2016 and January 2017, reported to the CNIL, compared two groups of malnourished patients: a group of refeeding patients (RP) and a group of non-refeeding patients (NRP). The inclusion criteria were weight loss of more than 10% or albuminemia less than 35g/L and RS risk factor. The primary endpoint was postoperative morbidity. The secondary endpoints were weight change and serum albumin over 6 months. Results: Seventy-three patients (30 RP and 43 NRP) were included. At the time of initial management, median weight loss was 18% [1-71], while albuminemia was 26g/L [13-40] in the RP group and 32.5g/L [32-48] in the NRP group (P=0.01). The overall postoperative morbidity rate was 88% (83% RP versus 90% NRP, P=0.47), and there was no significant difference between the 2 groups. The rate of anastomotic complications was 4% for RP versus 26% for NRP (P=0.03) after exclusion of liver surgery. Medium-term weight loss tended to be greater in RP (P=0.7). Nutritional support was continued until the third postoperative month in 13% of RPs vs. no NRPs (P=0.0002). Conclusion: After preoperative renutrition, we did not observe a decrease in morbidity but rather a decrease in the rate of anastomotic complications in favor of the RP group. This study underscores the middle-term importance of nutritional management in view of preserving the benefits of preoperative renutrition.
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Submitted on : Tuesday, June 30, 2020 - 11:07:04 AM
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Y. Loncar, T. Lefevre, L. Nafteux, L. Genser, G. Manceau, et al.. Intérêt de la nutrition préopératoire en chirurgie digestive pour des patients sévèrement dénutris : étude rétrospective.. Journal de Chirurgie Viscérale, Elsevier, 2020, 157 (2), pp.110-120. ⟨10.1016/j.jchirv.2019.03.070⟩. ⟨hal-02880279⟩



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