B cells and complement at the forefront of chemotherapy - Sorbonne Université
Journal Articles Nature Reviews Clinical Oncology Year : 2020

B cells and complement at the forefront of chemotherapy

Abstract

Effective anticancer therapies typically activate antitumour immunity, predominately mediated by T cells in the tumour microenvironment. Here, we discuss the roles of B cells and tertiary lymphoid structures in the context of chemotherapy-induced complement activation, which results in the induction of a B cell subset that modulates T cell function.
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Dates and versions

hal-02995715 , version 1 (09-11-2020)

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Catherine Sautès-Fridman, Lubka T Roumenina. B cells and complement at the forefront of chemotherapy. Nature Reviews Clinical Oncology, 2020, 17 (7), pp.393-394. ⟨10.1038/s41571-020-0376-0⟩. ⟨hal-02995715⟩
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