AIRR Community Guide to Planning and Performing AIRR-Seq Experiments - Sorbonne Université
Book Sections Year : 2022

AIRR Community Guide to Planning and Performing AIRR-Seq Experiments

Abstract

The development of high-throughput sequencing of adaptive immune receptor repertoires (AIRR-seq of IG and TR rearrangements) has provided a new frontier for in-depth analysis of the immune system. The last decade has witnessed an explosion in protocols, experimental methodologies, and computational tools. In this chapter, we discuss the major considerations in planning a successful AIRR-seq experiment together with basic strategies for controlling and evaluating the outcome of the experiment. Members of the AIRR Community have authored several chapters in this edition, which cover step-by-step instructions to successfully conduct, analyze, and share an AIRR-seq project.
Fichier principal
Vignette du fichier
10.1007%2F978-1-0716-2115-8_15.pdf (354.1 Ko) Télécharger le fichier
Origin Publisher files allowed on an open archive

Dates and versions

hal-03838024 , version 1 (06-04-2024)

Identifiers

Cite

Anne Eugster, Magnolia Bostick, Nidhi Gupta, Encarnita Mariotti-Ferrandiz, Gloria Kraus, et al.. AIRR Community Guide to Planning and Performing AIRR-Seq Experiments. Immunogenetics, 2453, Springer US, pp.261-278, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2115-8_15⟩. ⟨hal-03838024⟩
64 View
4 Download

Altmetric

Share

More